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1

Prefrontal cortex, caloric restriction and stress during aging: Studies on dopamine and acetylcholine release, BDNF and working memory

Alberto Del Arco, Gregorio Segovia, Marta de Blas, Pedro Garrido, Dario Acuña-Castroviejo, Reinald Pamplona, Francisco Mora

Journal:

Behavioural Brain Research

Year:

2011

Language:

english

File:

PDF, 1.09 MB

english, 2011

2

Restricción calórica y envejecimiento en humanos

Reinald Pamplona

Journal:

Revista Española de Geriatría y Gerontología

Year:

2009

File:

PDF, 185 KB

2009

3

Glicación de proteínas mitocondriales, estrés oxidativo y envejecimiento

Alba Naudí, Mariona Jové, Victoria Ayala, Manuel Portero-Otín, Reinald Pamplona

Journal:

Revista Española de Geriatría y Gerontología

Year:

2010

File:

PDF, 345 KB

2010

4

Modification of the longevity-related degree of fatty acid unsaturation modulates oxidative damage to proteins and mitochondrial DNA in liver and brain

Reinald Pamplona, Manel Portero-Otın, Alberto Sanz, J. Requena, Gustavo Barja

Journal:

Experimental Gerontology

Year:

2004

Language:

english

File:

PDF, 170 KB

english, 2004

5

La vida humana ante el proceso de envejecimiento

Reinald Pamplona

Journal:

Revista Española de Geriatría y Gerontología

Year:

2009

File:

PDF, 114 KB

2009

6

Restricción dietaria y envejecimiento: ¿una cuestión de calorías?

Reinald Pamplona

Journal:

Revista Española de Geriatría y Gerontología

Year:

2010

File:

PDF, 208 KB

2010

7

Fish oil and 3-thia fatty acid have additive effects on lipid metabolism but antagonistic effects on oxidative damage when fed to rats for 50 weeks

Natalya Filipchuk Vigerust, Daniel Cacabelos, Lena Burri, Kjetil Berge, Hege Wergedahl, Bjørn Christensen, Manuel Portero-Otin, Asgaut Viste, Reinald Pamplona, Rolf Kristian Berge, Bodil Bjørndal

Journal:

The Journal of Nutritional Biochemistry

Year:

2012

Language:

english

File:

PDF, 1.19 MB

english, 2012

8

Dietary intake of green tea polyphenols regulates insulin sensitivity with an increase in AMP-activated protein kinase α content and changes in mitochondrial respiratory complexes

Serrano, José C. E., Gonzalo-Benito, Hugo, Jové, Mariona, Fourcade, Stéphane, Cassanyé, Anna, Boada, Jordi, Delgado, Marco A., Espinel, Alberto E., Pamplona, Reinald, Portero-Otín, Manuel

Journal:

Molecular Nutrition & Food Research

Year:

2013

Language:

english

File:

PDF, 766 KB

english, 2013

9

Formation ofS-(carboxymethyl)-cysteine in rat liver mitochondrial proteins: effects of caloric and methionine restriction

NaudÃ, Alba, JovÃ©, Mariona, Cacabelos, Daniel, Ayala, Victoria, Cabre, Rosanna, Caro, Pilar, Gomez, JosÃ©, Portero-OtÃn, Manuel, Barja, Gustavo, Pamplona, Reinald

Journal:

Year:

2013

Language:

english

File:

PDF, 645 KB

english, 2013

10

Exceptionally old mice are highly resistant to lipoxidation-derived molecular damage

Lorena Arranz, Alba Naudí, Mónica De la Fuente, Reinald Pamplona

Journal:

Year:

2013

Language:

english

File:

PDF, 456 KB

english, 2013

11

Deregulation of purine metabolism in Alzheimer's disease

Ansoleaga, Belén, Jové, Mariona, Schlüter, Agatha, Garcia-Esparcia, Paula, Moreno, Jesús, Pujol, Aurora, Pamplona, Reinald, Portero-Otín, Manuel, Ferrer, Isidre

Journal:

Neurobiology of Aging

Year:

2015

Language:

english

File:

PDF, 2.01 MB

english, 2015

12

Metabolomics of Human Brain Aging and Age-Related Neurodegenerative Diseases

Jové, Mariona, Portero-Otín, Manuel, Naudí, Alba, Ferrer, Isidre, Pamplona, Reinald

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2014

Language:

english

File:

PDF, 4.79 MB

english, 2014

13

Mitochondria and Ageing

Leeuwenburgh, Christiaan, Pamplona, Reinald, Sanz, Alberto

Journal:

Journal of Aging Research

Year:

2011

Language:

english

File:

PDF, 55 KB

english, 2011

14

Altered glycolipid and glycerophospholipid signaling drive inflammatory cascades in adrenomyeloneuropathy

Ruiz, Montserrat, Jové, Mariona, Schlüter, Agatha, Casasnovas, Carlos, Villarroya, Francesc, Guilera, Cristina, Naudí, Alba, Pamplona, Reinald, Martinez, Ramón Gimeno, Fourcade, Stéphane, Portero-Otín

Journal:

Human Molecular Genetics

Year:

2015

Language:

english

File:

PDF, 1.49 MB

english, 2015

15

Obesity changes the human gut mycobiome

Mar Rodríguez, M., Pérez, Daniel, Javier Chaves, Felipe, Esteve, Eduardo, Marin-Garcia, Pablo, Xifra, Gemma, Vendrell, Joan, Jové, Mariona, Pamplona, Reinald, Ricart, Wifredo, Portero-Otin, Manuel, Ch

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.87 MB

english, 2015

16

Mediterranean diet, physical activity and subcutaneous advanced glycation end-products’ accumulation: a cross-sectional analysis in the ILERVAS project

Sánchez, Enric, Betriu, Àngels, Salas-Salvadó, Jordi, Pamplona, Reinald, Barbé, Ferrán, Purroy, Francesc, Farràs, Cristina, Fernández, Elvira, López-Cano, Carolina, Mizab, Chadia, Lecube, Albert

Journal:

European Journal of Nutrition

Year:

2019

Language:

english

File:

PDF, 890 KB

english, 2019

17

Succination of Protein Thiols in Human Brain Aging

JovÃ©, Mariona, Pradas, Irene, Mota-Martorell, Natalia, CabrÃ©, Rosanna, Ayala, Victoria, Ferrer, Isidre, Pamplona, Reinald

Journal:

Frontiers in Aging Neuroscience

Year:

2020

Language:

english

File:

PDF, 1.77 MB

english, 2020

18

Antioxidants halt axonal degeneration in a mouse model of X-adrenoleukodystrophy

Jone López-Erauskin, Stéphane Fourcade, Jorge Galino, Montserrat Ruiz, Agatha Schlüter, Alba Naudi, Mariona Jove, Manuel Portero-Otin, Reinald Pamplona, Isidre Ferrer, Aurora Pujol

Journal:

Annals of Neurology

Year:

2011

Language:

english

File:

PDF, 708 KB

english, 2011

19

Cell stress induces TDP-43 pathological changes associated with ERK1/2 dysfunction: implications in ALS

Victòria Ayala, Ana Belén Granado-Serrano, Daniel Cacabelos, Alba Naudí, Ekaterina V. Ilieva, Jordi Boada, Víctor Caraballo-Miralles, Jerònia Lladó, Isidro Ferrer, Reinald Pamplona, Manuel Portero-Oti

Journal:

Acta Neuropathologica

Year:

2011

Language:

english

File:

PDF, 1.31 MB

english, 2011

20

Effect of graded corticosterone treatment on aging-related markers of oxidative stress in rat liver mitochondria

Pilar Caro, José Gómez, Alberto Sanz, Manel Portero-Otín, Reinald Pamplona, Gustavo Barja

Journal:

Year:

2007

Language:

english

File:

PDF, 199 KB

english, 2007

21

Effect of 8.5% and 25% caloric restriction on mitochondrial free radical production and oxidative stress in rat liver

José Gómez, Pilar Caro, Alba Naudí, Manuel Portero-Otin, Reinald Pamplona, Gustavo Barja

Journal:

Year:

2007

Language:

english

File:

PDF, 316 KB

english, 2007

22

Forty percent and eighty percent methionine restriction decrease mitochondrial ROS generation and oxidative stress in rat liver

Pilar Caro, José Gómez, Mónica López-Torres, Inés Sánchez, Alba Naudí, Mariona Jove, Reinald Pamplona, Gustavo Barja

Journal:

Year:

2008

Language:

english

File:

PDF, 410 KB

english, 2008

23

Effect of 40% restriction of dietary amino acids (except methionine) on mitochondrial oxidative stress and biogenesis, AIF and SIRT1 in rat liver

Pilar Caro, Jose Gomez, Inés Sanchez, Ruben Garcia, Monica López-Torres, Alba Naudí, Manuel Portero-Otin, Reinald Pamplona, Gustavo Barja

Journal:

Year:

2009

Language:

english

File:

PDF, 308 KB

english, 2009

24

An evolutionary comparative scan for longevity-related oxidative stress resistance mechanisms in homeotherms

Reinald Pamplona, Gustavo Barja

Journal:

Year:

2011

Language:

english

File:

PDF, 1.80 MB

english, 2011

25

Effect of methionine dietary supplementation on mitochondrial oxygen radical generation and oxidative DNA damage in rat liver and heart

Jose Gomez, Pilar Caro, Ines Sanchez, Alba Naudi, Mariona Jove, Manuel Portero-Otin, Monica Lopez-Torres, Reinald Pamplona, Gustavo Barja

Journal:

Journal of Bioenergetics and Biomembranes

Year:

2009

Language:

english

File:

PDF, 239 KB

english, 2009

26

Forty percent methionine restriction lowers DNA methylation, complex I ROS generation, and oxidative damage to mtDNA and mitochondrial proteins in rat heart

Ines Sanchez-Roman, Alexia Gomez, Jose Gomez, Henar Suarez, Carlota Sanchez, Alba Naudi, Victoria Ayala, Manuel Portero-Otin, Monica Lopez-Torres, Reinald Pamplona, Gustavo Barja

Journal:

Journal of Bioenergetics and Biomembranes

Year:

2011

Language:

english

File:

PDF, 224 KB

english, 2011

27

Protein and lipid oxidative damage and complex I content are lower in the brain of budgerigar and canaries than in mice. Relation to aging rate

Reinald Pamplona, Manuel Portero-Otín, Alberto Sanz, Victoria Ayala, Ekaterina Vasileva, Gustavo Barja

Journal:

Year:

2005

Language:

english

File:

PDF, 398 KB

english, 2005

28

Correlation of fatty acid unsaturation of the major liver mitochondrial phospholipid classes in mammals to their maximum life span potential

Manuel Portero-Otín, Maria Josep Bellumunt, Maria Cristina Ruiz, Gustavo Barja, Reinald Pamplona

Journal:

Year:

2001

Language:

english

File:

PDF, 108 KB

english, 2001

29

Biomarkers of aging in Drosophila

Jake Jacobson, Adrian J. Lambert, Manuel Portero-Otín, Reinald Pamplona, Tapiwanashe Magwere, Satomi Miwa, Yasmine Driege, Martin D. Brand, Linda Partridge

Journal:

Year:

2010

Language:

english

File:

PDF, 864 KB

english, 2010

30

Membrane Fatty Acid Unsaturation, Protection against Oxidative Stress, and Maximum Life Span : A Homeoviscous-longevity Adaptation?

REINALD PAMPLONA, GUSTAVO BARJA, MANUEL PORTERO-OTÍN

Journal:

Annals of the New York Academy of Sciences

Year:

2002

Language:

english

File:

PDF, 501 KB

english, 2002

31

Mitochondrial ATP-Synthase in the Entorhinal Cortex Is a Target of Oxidative Stress at Stages I/II of Alzheimer's Disease Pathology

Beatrice Terni, Jordi Boada, Manuel Portero-Otin, Reinald Pamplona, Isidro Ferrer

Journal:

Brain Pathology

Year:

2010

Language:

english

File:

PDF, 640 KB

english, 2010

32

Protein Targets of Oxidative Damage in Human Neurodegenerative Diseases with Abnormal Protein Aggregates

Anna Martínez, Manuel Portero-Otin, Reinald Pamplona, Isidre Ferrer

Journal:

Brain Pathology

Year:

2010

Language:

english

File:

PDF, 155 KB

english, 2010

33

Maillard Reaction versus Other Nonenzymatic Modifications in Neurodegenerative Processes

Reinald Pamplona, Ekaterina Ilieva, Victoria Ayala, Maria Josep Bellmunt, Daniel Cacabelos, Esther Dalfo, Isidre Ferrer, Manuel Portero-Otin

Journal:

Annals of the New York Academy of Sciences

Year:

2008

Language:

english

File:

PDF, 104 KB

english, 2008

34

Advanced lipoxidation end-products

Reinald Pamplona

Journal:

Chemico-Biological Interactions

Year:

2011

Language:

english

File:

PDF, 383 KB

english, 2011

35

25.2. Lipoxidative damage in the comparative biology of aging

Reinald Pamplona

Journal:

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology

Year:

2007

Language:

english

File:

PDF, 94 KB

english, 2007

36

Protein nonenzymatic modifications and proteasome activity in skeletal muscle from the short-lived rat and long-lived pigeon

Manel Portero-Otín, Jesús R. Requena, Maria Josep Bellmunt, Victoria Ayala, Reinald Pamplona

Journal:

Experimental Gerontology

Year:

2004

Language:

english

File:

PDF, 272 KB

english, 2004

37

Increased oxidation, glycoxidation, and lipoxidation of brain proteins in prion disease

Reinald Pamplona, Alba Naudí, Rosalina Gavín, Miguel A. Pastrana, Gustavo Sajnani, Ekaterina V. Ilieva, José Antonio del Río, Manuel Portero-Otín, Isidre Ferrer, Jesús R. Requena

Journal:

Free Radical Biology and Medicine

Year:

2008

Language:

english

File:

PDF, 668 KB

english, 2008

38

Depletion of oxidative and endoplasmic reticulum stress regulators in Pick disease

Ekaterina V. Ilieva, Alba Naudí, Anton Kichev, Isidre Ferrer, Reinald Pamplona, Manuel Portero-Otín

Journal:

Free Radical Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 1.18 MB

english, 2010

39

Age-related changes in brain mitochondrial DNA deletion and oxidative stress are differentially modulated by dietary fat type and coenzyme Q10

Julio J. Ochoa, Reinald Pamplona, M. Carmen Ramirez-Tortosa, Sergio Granados-Principal, Patricia Perez-Lopez, Alba Naudí, Manuel Portero-Otin, Magdalena López-Frías, Maurizio Battino, José L. Quiles

Journal:

Free Radical Biology and Medicine

Year:

2011

Language:

english

File:

PDF, 592 KB

english, 2011

40

Advanced glycation end products in urine: Are some sugar-derived products better than others?

Reinald Pamplona, Manuel Portero-Otin

Journal:

Journal of Laboratory and Clinical Medicine

Year:

2004

Language:

english

File:

PDF, 31 KB

english, 2004

41

Effect of ageing and caloric restriction on specific markers of protein oxidative damage and membrane peroxidizability in rat liver mitochondria

Adrian J. Lambert, Manuel Portero-Otin, Reinald Pamplona, Brian J. Merry

Journal:

Mechanisms of Ageing and Development

Year:

2004

Language:

english

File:

PDF, 406 KB

english, 2004

42

Protein methionine content and MDA-lysine adducts are inversely related to maximum life span in the heart of mammals

Maria Cristina Ruiz, Victoria Ayala, Manel Portero-Otín, Jesús R. Requena, Gustavo Barja, Reinald Pamplona

Journal:

Mechanisms of Ageing and Development

Year:

2005

Language:

english

File:

PDF, 248 KB

english, 2005

43

Coenzyme Q addition to an n-6 PUFA-rich diet resembles benefits on age-related mitochondrial DNA deletion and oxidative stress of a MUFA-rich diet in rat heart

José L. Quiles, Reinald Pamplona, M. Carmen Ramirez-Tortosa, Alba Naudí, Manuel Portero-Otin, Eduardo Araujo-Nepomuceno, Magdalena López-Frías, Maurizio Battino, Julio J. Ochoa

Journal:

Mechanisms of Ageing and Development

Year:

2010

Language:

english

File:

PDF, 488 KB

english, 2010

44

Effect of the degree of fatty acid unsaturation of rat heart mitochondria on their rates of H2O2 production and lipid and protein oxidative damage

Asunción Herrero, Manuel Portero-Otı́n, Marı́a Josep Bellmunt, Reinald Pamplona, Gustavo Barja

Journal:

Mechanisms of Ageing and Development

Year:

2001

Language:

english

File:

PDF, 190 KB

english, 2001

45

Oxidative, glycoxidative and lipoxidative damage to rat heart mitochondrial proteins is lower after 4 months of caloric restriction than in age-matched controls

Reinald Pamplona, Manuel Portero-Otı́n, Jesus Requena, Ricardo Gredilla, Gustavo Barja

Journal:

Mechanisms of Ageing and Development

Year:

2002

Language:

english

File:

PDF, 173 KB

english, 2002

46

Thyroid status modulates glycoxidative and lipoxidative modification of tissue proteins

Reinald Pamplona, Manel Portero-Otı́n, Cristina Ruiz, Maria Josep Bellmunt, Jesús R Requena, Suzanne R Thorpe, John W Baynes, Marı́a Romero, Mónica López-Torres, Gustavo Barja

Journal:

Free Radical Biology and Medicine

Year:

1999

Language:

english

File:

PDF, 256 KB

english, 1999

47

Carboxymethylated phosphatidylethanolamine in mitochondrial membranes of mammals : Evidence for intracellular lipid glycoxidation

Reinald Pamplona, Jesús R. Requena, Manuel Portero-Otín, Joan Prat, Suzanne R. Thorpe, Maria Josep Bellmunt

Journal:

Year:

1998

Language:

english

File:

PDF, 136 KB

english, 1998

48

Chromatographic evidence for amadori product formation in rat liver aminophospholipids

Reinald Pamplona, M.Josep Bellmunt, Manel Portero, David Riba, Joan Prat

Journal:

Year:

1995

Language:

english

File:

PDF, 455 KB

english, 1995

49

Correlation of plasma lipid fractions with colorimetrically determined glycated hemoglobin in a nondiabetic population

Joan Prat, Reinald Pamplona, Albert Sorribas, Silvestre Martin, Marce Viñallonga, Ramón Segura

Journal:

Year:

1989

Language:

english

File:

PDF, 857 KB

english, 1989

50

Evidence for the Maillard reaction in rat lung collagen and its relationship with solubility and age

M.Josep Bellmunt, Manel Portero, Reinald Pamplona, Luana Cosso, Patrizio Odetti, Joan Prat

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

1995

Language:

english

File:

PDF, 753 KB

english, 1995